Cellular Repair – UmiWell

NAD reloaded: Hacking bacterial defenses

A bstract.Nicotinamide adenine dinucleotide (NAD) is an essential metabolite, and its depletion serves as a common bacterial immune strategy against bacteriophages (phages). In a recent…

UmiWellDecember 30, 2024

Cellular Repair DNA Repair

NMNAT2 is a druggable target to drive neuronal NAD production

A bstract. Maintenance of NAD pools is critical for neuronal survival. The capacity to maintain NAD pools declines in neurodegenerative disease. We identify that low…

UmiWellDecember 30, 2024

Cellular Repair

The Role of NAD+ in Regenerative Medicine

The scientific community now recognizes aging as a modifiable process that can be slowed or even reversed, heralding a new era of cellular regenerative medicine…

UmiWellMay 1, 2024

Cellular Repair

NAD+ Precursors and Bile Acid Treat Enteric Dysfunction

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UmiWellJanuary 15, 2024

Cellular Repair

Trigonelline Boosts Muscle Function and Declines in Aging

A bstract Mitochondrial dysfunction and low NAD+ levels are markers of skeletal muscle aging and sarcopenia. This study links circulating trigonelline, related to nicotinic acid,…

UmiWellJanuary 7, 2024