Metabolism – UmiWell

NAD reloaded: Hacking bacterial defenses

A bstract.Nicotinamide adenine dinucleotide (NAD) is an essential metabolite, and its depletion serves as a common bacterial immune strategy against bacteriophages (phages). In a recent…

UmiWellDecember 30, 2024

Metabolism

NAD+ Boost Eases Heart Failure via SDR

The study examines the effects of increasing cellular NAD+ levels on heart failure. Cardiac dysfunction was induced in SIRT3-deficient mice and compared with wild-type mice…

UmiWellApril 16, 2024

Metabolism

NAD+ homeostasis in health and disease

The conceptual evolution of nicotinamide adenine dinucleotide (NAD+) from being seen as a simple metabolic cofactor to a pivotal cosubstrate for proteins regulating metabolism and…

UmiWellFebruary 22, 2024

Metabolism

NAD+ repletion with niacin counteracts cancer cachexia

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UmiWellJanuary 8, 2024

Metabolism

NAD+ Regulates Metabolism and DNA Replication

A bstract The complex interplay of enzymatic processes involving nicotinamide adenine dinucleotide (NAD+) is crucial for the maintenance of metabolic equilibrium and genomic stability. As…

UmiWellNovember 13, 2023